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Indiana University Scientist Works to Detach Protein that HIV Uses as Protective Shield

February 13, 2012 -- One of the frustrations for scientists working on HIV/AIDS treatments has been the human immunodeficiency virus’ ability to evade the body’s immune system. Now an Indiana University researcher is testing a compound developed by a Harvard University colleague that could help put the immune system back in the hunt.  read more...

IU Researchers Join National Network Testing Stem Cell Therapies for Cardiovascular Disease

April 2, 2012 -- Physician scientists at the Indiana University School of Medicine have been selected to join the nationwide Cardiovascular Cell Therapy Research Network and will begin a new round of tests of adult stem cell treatments for peripheral artery disease this summer.  read more...

Alcohol and Drug “Cues” Trigger Physical Responses that Cause Cravings and Relapse, IU Researchers Report

April 16, 2012 -- Alcohol craving and relapse may have a physical neurological basis, and a particular part of the brain goes into action when those cravings are stimulated, Indiana University School of Medicine researchers reported today.  read more...

Scientists Induce Heart Structural Cells to Become Working Heart Muscle After Damage

April 18, 2012 -- Scientists have reprogrammed heart scar tissue cells in mice into working heart muscle cells, an accomplishment that holds out hope for future regeneration techniques, according to a report by researchers from the University of California, San Francisco, and Indiana University School of Medicine.  read more...

Indiana University Researchers Extract Viable DNA from Decades-Old Preserved Tissue

April 24, 2012 -- DNA viable for clinical and experimental research can be extracted from tissue preserved many decades ago, according to a study published by Indiana University School of Medicine researchers. The ability to extract viable DNA data from historic tissue samples may contribute to the development of innovative, individualized therapies for individuals with psychological illnesses.  read more...

Awards to five IU School of Medicine physicians address critical need for geriatricians

April 27, 2012 -- Five Indiana University School of Medicine geriatricians are among only 83 advanced fellows and junior faculty members nationwide who will share in $2.5 million in career development awards from The John A. Hartford Foundation. The IU School of Medicine was one of the top-funded institutions.  read more...

Institute of Medicine Urges Improved FDA Monitoring of Drugs After Market Approval

May 1, 2012 -- The U.S. Food and Drug Administration should adopt a more systematic approach to tracking potential problems with prescription drugs after they are approved, an Institute of Medicine committee said Tuesday in a report coauthored by an Indiana University bioethics expert.  read more...

Indiana CTSI releases progress report to highlight growth

May 2, 2012 -- An institute established four years ago with a multimillion-dollar grant from the National Institutes of Health announced that it has distributed more than $12.5 million in grants and awards to support research since 2008 and currently supports more than 80 full-time equivalent professional jobs across Indiana.  read more...

Bioethics experts announce global research platform to tackle ethical, legal and social issues in genomics

May 10, 2012 -- Just as the sequencing of the human genome is having a pervasive and global impact on medicine, work on the societal impact of the genomic revolution must also move to an international stage, a team of bioethics experts said today.  read more...

Individuals With Dementia More Likely to Die at Home Than in Nursing Homes

May 14, 2012 -- A new study from the Regenstrief Institute and Indiana University has found that, at time of death, individuals with dementia are more likely to be living at home than in a nursing home. This contradicts the commonly held view that most individuals with dementia in the United States eventually move to nursing homes and die there.  read more...

Researchers identify key genes and prototype predictive test for schizophrenia

May 15, 2012 -- An Indiana University-led research team, along with a group of national and international collaborators, has identified and prioritized a comprehensive group of genes most associated with schizophrenia that together can generate a score indicating whether an individual is at higher or lower risk of developing the disease.  read more...

Olanzapine controls breakthrough chemotherapy-induced nausea and vomiting

May 17, 2012 -- Cancer patients who suffer chemotherapy-induced nausea and vomiting are experiencing effective relief as a result of new Indiana University research indicating the usefulness of the anti-psychotic olanzapine to control these potentially debilitating side effects.  read more...

STeleR study: Telerehab improves functioning after stroke

May 29, 2012 -- Researchers led by Regenstrief Institute investigator Neale Chumbler, Ph.D., a research scientist with the Center of Excellence on Implementing Evidence-Based Practice at the Richard Roudebush VA Medical Center in Indianapolis, have developed STeleR, a home telerehabilitation program that they report improves lower body physical functioning even two years after a stroke. Participating in STeleR also increased the likelihood of maintaining a regular fitness routine, enhanced money management skills, and improved the capability to prepare meals and take care of personal needs such as bathing.  read more...

Intravenous kidney cell transplant experiments raise hope for future human kidney failure treatments

May 30, 2012 -- Indiana University School of Medicine scientists have successfully transplanted primary kidney cells intravenously to treat renal failure in rats, pointing the way to a possible future alternative to kidney transplants and expensive dialysis treatments in humans.  read more...

IU research leads to risk factor test for rare chest cancers

June 4, 2012 -- Research conducted by physicians and scientists at the Indiana University School of Medicine has resulted in a genetic test to predict the risk of recurrence of thymoma, a rare tumor of the upper chest. The study results were presented June 2 in a poster presentation at the 2012 American Society of Clinical Oncology Annual Meeting in Chicago.  read more...

Analysis will examine safety of in-hospital underwater births

June 7, 2012 -- One of the first systematic examinations of the safety of in-hospital underwater births in the United States commences this month, when Regenstrief Institute fellow Jeanne Ballard, M.D., an obstetrician/gynecologist with more than 16 years of experience delivering babies, collaborates with Regenstrief investigator Michael Weiner, M.D., MPH to put the tools of medical informatics and outcomes research to work to improve reproductive health care.  read more...

Study: Free, user-friendly 'blood pressure cuff' for dementia is reliable and valid

June 14, 2012 -- A new study shows that a practical clinical tool developed by researchers from the Regenstrief Institute and the Indiana University School of Medicine to measure severity of dementia symptoms is reliable and valid. The Healthy Aging Brain Care Monitor is simple, user-friendly and sensitive to change in symptoms.  read more...

Study: Willingness to be screened for dementia varies by age but not by sex, race or income

June 19, 2012 -- The first study to examine the actual willingness of older adults to be screened for dementia has found that acceptance of screening is pervasive, although it varies by age. However, willingness to be screened for dementia does not differ by sex, race or income level.  read more...

Funding renewed for IU-Kenya international research ethics partnership

June 20, 2012 -- An international bioethics program at Indiana University and Moi University in Kenya has been renewed for five years with a $1.25 million grant from the Fogarty International Center at the National Institutes of Health to the IU Center for Bioethics.  read more...

Wishard and St. Vincent physicians honored at White House event

June 20, 2012 -- Lisa Harris, M.D., CEO and medical director for Wishard Health Services, was one of 82 health care providers nationwide recognized for their program in health IT by the White House and Health and Human Services at a Health IU Town Hall in Washington, D.C., June 19.  read more...

IU scientist to lead study on the use of telehealth to assist veterans with mild brain injury

June 26, 2012 -- An Indiana University researcher has received a grant from the U.S. Department of Veterans Affairs to develop a new assessment mechanism that will improve long-distance care for military veterans with mild traumatic brain injury. The system will be piloted at five hospitals serving veterans and active-duty soldiers in the South and Midwest, including the Walter Reed National Military Medical Center in Bethesda, Md.  read more...

Scientists mount genome research initiative to unlock Alzheimer’s genetic secrets

July 2, 2012 -- The genetic secrets of Alzheimer’s disease are hiding in our DNA. Researchers at Indiana University School of Medicine and colleagues across the country are mounting a revolutionary new research project to find them.  read more...

Glick Eye Institute researcher lands NIH funding to study racial disparities in glaucoma

July 12, 2012 -- Why do people of African descent develop glaucoma at rates higher than Caucasians? Funding from the National Institutes of Health will help Alon Harris, M.S., Ph.D., FARVO, director of clinical research at the Eugene and Marilyn Glick Eye Institute, learn the answer to that question.  read more...

Pediatric ophthalmologist designs vision screening kit for schools, physicians

July 16, 2012 -- Daniel Neely, M.D., treats children in his pediatric ophthalmology clinic for vision problems ranging from amblyopia and strabismus to cataracts and retinoblastoma. By the time children reach his exam chair, they could be at risk for serious eye conditions.  read more...

Indiana University fibromyalgia study seeks participants

July 19, 2012 -- The Indiana University School of Medicine Division of Rheumatology seeks participants for a study of an oral allergy medication to improve the symptoms of fibromyalgia.  read more...

IU researchers identify protein target that could lead to therapies for hard-to-treat cancers

July 23, 2012 -- Researchers at the Indiana University School of Medicine have identified a compound that targets a cancer-related protein, suggesting it could offer a future therapy for difficult-to-treat cancers.  read more...

Army anti-suicide initiative brings $3 million to IU School of Medicine scientist’s research

July 24, 2012 -- Could a nasal spray provide a quick antidote to suicidal thoughts among soldiers? An Indiana University School of Medicine scientist has been awarded a $3 million research grant from the U.S. Army to develop such a system.  read more...

Study: Group yoga improves motor function and balance long after stroke

July 27, 2012 -- Group yoga can improve motor function and balance in stroke survivors, even if they don’t begin yoga until six months or more after the stroke, according to “Post-Stroke Balance Improves With Yoga: A Pilot Study,” published online July 26 in the journal Stroke.  read more...

Indiana University imaging study of addiction risk factors needs young volunteers

August 1, 2012 -- The Indiana University School of Medicine is seeking volunteers for an imaging study that may shed light on why some children are more prone to develop substance abuse problems later in life.  read more...

Groundbreaking ceremony set as construction begins on IU neurosciences research facility

August 3, 2012 -- Indiana Gov. Mitch Daniels will join leaders of Indiana University and Indiana University Health Aug. 6 to recognize the start of construction that will result in a new center for research and clinical excellence in the neurosciences in Indianapolis.  read more...

Blocking immune system receptor present on neurons could improve morphine effectiveness, IU scientists report

August 16, 2012 -- Morphine given to relieve chronic pain can, counter to expectations, result in a person feeling more pain. But a drug that blocks a key immune system component could make the morphine treatment more effective by blocking that side-effect pain, according to researchers at Indiana University School of Medicine.  read more...

External Advisory Council formed to assist with search for IU School of Medicine dean

August 31, 2012 -- An External Advisory Council has been appointed by President Michael A. McRobbie to assist the recently formed search committee in identifying finalists for the next dean of the Indiana University School of Medicine and vice president for university clinical affairs.  read more...

Review: Altruism's influence on parental decision to vaccinate children is unclear

September 11, 2012 -- As outbreaks of preventable diseases such as whooping cough and measles increase in the United States, researchers from the Regenstrief Institute and Indiana University School of Medicine are investigating whether altruism, known to influence adults’ decisions to immunize themselves, influences parental decisions to vaccinate their children.  read more...

IU School of Medicine and IU Health collaborate on cardiovascular genetics in patient care, research

September 11, 2012 -- With funding from the Strategic Research Initiative, physician-scientists at the Indiana University School of Medicine and Indiana University Health are implementing the state’s first comprehensive program to implement genetic testing in research and clinical care in heart disease  read more...

Translation of research into practice for post-stroke care goes national

September 13, 2012 -- Researcher-clinicians from the Regenstrief Institute, the Department of Veterans Affairs and Indiana University School of Medicine are leading a national effort to coordinate and organize acute stroke care across the entire VA medical system. This initiative to improve in-hospital management of stroke with the goal of reducing disability and death was implemented by the VA this summer and may serve as a model for public and private hospital systems around the country.  read more...

Study provides roadmap for delirium risks, prevention, treatment, prognosis and research

September 18, 2012 -- Delirium, a common acute condition with significant short- and long-term effects on cognition and function, should be identified as an indicator of poor long-term prognosis, prompting immediate and effective management strategies, according to the authors of a new systematic evidence review.  read more...

IU School of Medicine, Rehabilitation Hospital of Indiana selected for national brain injury research network

September 27, 2012 -- Federal officials have designated Indiana University School of Medicine and Rehabilitation Hospital of Indiana a Traumatic Brain Injury Model System site. The five-year $2,137,500 grant adds local researchers and physicians to the leading national network of centers studying and treating traumatic brain injury and its impact on the lives of patients and their families.  read more...

Glick Eye Institute researcher honored with Ausich scholarship

October 11, 2012 -- Halesha Basavarajappa, a Ph.D. student working in a research lab at the Eugene and Marilyn Glick Eye Institute, has received a two-year $30,000 Ausich Graduate Student Research Scholarship from Kemin Health.  read more...

IU School of Medicine researcher: Genome Atlas finds future targets for breast cancer treatments

October 23, 2012 -- Scientists are now a step closer to understanding the complexities of breast cancer with findings made available through The Cancer Genome Atlas, a multi-center study funded by the National Institutes of Health. Indiana University School of Medicine participated in the research that identified four molecular cancer subtypes based on samples from 825 breast cancer patients.  read more...

Indiana University researchers report first effective treatment of tumors arising from common genetic disease NF1

November 1, 2012 -- Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially life-threatening tumors often found in children.  read more...

Joining Forces with Indiana University School of Medicine: Working for veterans

November 8, 2012 -- Indiana University School of Medicine is serving veterans through research initiatives focusing on health problems affecting those who have served and their families.  read more...

Regenstrief health care delivery contest seeks ideas from the public to propel research

November 15, 2012 -- How can we ensure that the scientific community is asking the right questions about how to deliver the best health care to Americans? The Regenstrief Institute, an internationally recognized health care research organization, is seeking input for future studies from the public, whose varied voices are typically underrepresented in research.  read more...

IU scientist will use $1.15M grant to research biomarkers for heavy drinking

November 15, 2012 -- An Indiana University researcher has received a $1.15 million Department of Defense grant to investigate whether a simple blood test could be used to determine whether a person has recently been drinking heavily.  read more...

Inhibition of enzyme could lead to improved chemotherapy and stem cell transplant results

November 21, 2012 -- Blocking the action of one enzyme could mean improved results for thousands of cancer patients who undergo bone marrow or cord blood transplants after chemotherapy, an Indiana University research team has reported.  read more...

Regenstrief Institute and Merck launch unique post-doctoral training opportunity

November 27, 2012 -- The Regenstrief Institute, in collaboration with Merck, has created two visiting scholar positions to provide post-doctoral training at the intersection of pharmacoepidemiology and biomedical informatics at the institute.  read more...

Frankel to lead first IU Simon Cancer Center Palliative Care Research and Education Program

December 5, 2012 -- Research sociologist Richard M. Frankel, Ph.D., has been selected to be the first director of the Mary Margaret Walther Palliative Care Research and Education Program at the Indiana University Melvin and Bren Simon Cancer Center.  read more...

Husband, wife join Glick Eye Institute as basic science research director, Marilyn K. Glick Senior Chair

January 11, 2013 -- Vision research at the Eugene and Marilyn Glick Eye Institute will receive a double boost when husband-and-wife research scientists from the University of Florida join the Department of Ophthalmology at the Indiana University School of Medicine this year.  read more...

IU researcher’s lung cancer work may someday improve standard of care

January 23, 2013 -- Lung cancer researchers at Indiana University Melvin and Bren Simon Cancer Center are developing new anti-cancer agents that may someday improve the current standard of care.  read more...

IU School of Medicine study: Common anti-fever medications pose kidney injury risk for children

January 25, 2013 -- Sick children, especially those with some dehydration from flu or other illnesses, risk significant kidney injury if given drugs such as ibuprofen and naproxen, Indiana University School of Medicine researchers said Friday.  read more...

McAllister to lead Indiana University psychiatry program

January 25, 2013 -- Thomas W. McAllister, M.D., has been named chair of the Department of Psychiatry and the Albert Eugene Sterne Professor of Clinical Psychiatry at Indiana University School of Medicine. He will begin his duties this summer, pending approval by the IU Board of Trustees.  read more...

Cryptic Masons Medical Research Foundation continues vascular research support at IU School of Medicine

January 31, 2013 -- The Cryptic Masons Medical Research Foundation provided nearly $200,000 in support for research at Indiana University School of Medicine in 2012, school officials said, pushing their aggregated commitment to more than $3 million, with a promise for ongoing major support.  read more...

Fish oil may protect dialysis patients from sudden cardiac death

February 6, 2013 -- Medical literature long has touted the benefits of omega-3 fatty acids for the heart. But until now, researchers have not studied the potential benefit for people on hemodialysis, who are among the highest-risk patients for sudden cardiac death.  read more...

On 'Sound Medicine': Changes for Medicare, fecal transplants, and studying stress to predict health

February 8, 2013 -- The award-winning “Sound Medicine” announces its program for Feb. 10, featuring a doc chat on the potential impact of health care law on the states, a look at how some of Detroit’s homeless are getting critical medical care, and how our responses to stress today will affect our health in 10 years.  read more...

On 'Sound Medicine': African childbirth mortality, brain surgery, and early puberty in boys

February 15, 2013 -- The award-winning “Sound Medicine” announces its program for Feb. 17, featuring several segments on brain surgery breakthroughs, adherence devices and early puberty in boys. Please check local listings for broadcast dates, times and stations.  read more...

Women with polycystic ovary syndrome seem to have higher risk of heart attack and stroke

February 18, 2013 -- A syndrome common in women of reproductive age may place them at greater risk for hardening of the arteries, which predisposes them to heart attack and stroke, according to research published Feb. 15 in the American Journal of Physiology, Endocrinology and Metabolism.  read more...

Genome-wide imaging study identifies new gene associated with Alzheimer’s plaques

February 20, 2013 -- A study combining genetic data with brain imaging, designed to identify genes associated with the amyloid plaque deposits found in Alzheimer’s disease patients, has not only identified the APOE gene -- long associated with development of Alzheimer’s -- but has uncovered an association with a second gene, called BCHE.  read more...

For top athletes, NFL Scouting Combine begins with heart screening

February 21, 2013 -- For more than 300 college football players, the NFL Scouting Combine that runs through Tuesday at Lucas Oil Stadium is a prime opportunity to show that they have what it takes to join the ranks of the National Football League.  read more...

On 'Sound Medicine': Healthy soldiers, the latest cardiac innovations, and adult ADHD

February 21, 2013 -- The award-winning “Sound Medicine” announces its program for Feb. 24, with segments covering adult ADHD, the latest cardiac innovations, and a new treatment for uncontrolled hypertension. Please check local listings for broadcast dates, times and stations.  read more...

Regenstrief presentation: Collaborating to improve health care delivery in Rwanda

February 28, 2013 -- Investigators from the Regenstrief Institute will demonstrate the groundbreaking Open Health Information Exchange or OpenHIE, currently deployed in Rwanda at the Healthcare Information and Management Systems Society, or HIMSS, annual conference March 3 to 7 in New Orleans.  read more...

Study: Computerized reminders significantly improve HIV care in resource-limited setting

March 7, 2013 -- A large randomized controlled study is among the first to rigorously demonstrate that health information technology can improve compliance with patient care guidelines by clinicians in resource-limited countries. The study was led by Regenstrief Institute investigator Martin Chieng Were, M.D., M.S., assistant professor of medicine at the Indiana University School of Medicine, and Regenstrief Institute affiliated scientist Rachel Vreeman, M.D., M.S, assistant professor of pediatrics at the IU School of Medicine.  read more...

NIH funding puts researchers on path to restoring vision loss from diabetic eye disease

March 12, 2013 -- Researchers at the Eugene and Marilyn Glick Eye Institute and the Indiana Center for Vascular Biology at Indiana University School of Medicine are on the cusp of perfecting stem cell treatments that would halt – and potentially reverse – vision loss caused by diabetic retinopathy.  read more...

Researchers say NSAIDs can boost stem cells for transplants for cancer patients

March 13, 2013 -- Scientists say that non-steroidal anti-inflammatory drugs may be a boon to doctors gathering stem cells for transplants to treat patients with blood or bone marrow cancers, including non-Hodgkin’s lymphoma and multiple myeloma.  read more...

Cancer researchers discover new type of retinoblastoma in babies

March 13, 2013 -- Not all forms of retinoblastoma, a pediatric cancer of the eye, may be inherited, a discovery that would spare children years of medical evaluations and offer the potential of drug therapy for an aggressive malignancy.  read more...
 

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